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Clinical significance of IL-6, IL-2 and TNF-αdetections in patients with cerebral infarction

Wei Qi Fan

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Abstract

Objecive to investigate the changes and clinical significance of serum IL-6, IL-2 and TNF-α in patients with acute cerebral infarction. Methods ELISA was applied to measure serum levels of IL-6,IL-2 and TNF-α in 30 cerebral infarction patients at acute stage and at convalescent stage, and the results were compared with those in 32 healthy controls. Results Serum levels of IL-6,IL-2 and TNF-α in the patients were significantly highter than that in the controls(P0.01), the levels in acute stage were highter than that in convalescent stage(P0.05). Conclusions Serum IL-6, IL-2 and TNF-α in the process of the development of cerebral infarction play important roles, and their levels can be used in the differential diagnosis of cerebral infarction with acute stage and convalescent stage.

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What this paper is about

Objecive to investigate the changes and clinical significance of serum IL-6, IL-2 and TNF-α in patients with acute cerebral infarction. Methods ELISA was applied to measure serum levels of IL-6,IL-2 and TNF-α in 30 cerebral infarction patients at acute stage and at convalescent stage, and the results were compared with those in 32 healthy controls. Results Serum levels of IL-6,IL-2 and TNF-α in the patients were significantly highter than that in the controls(P0.01), the levels in acute stage were highter than that in convalescent stage(P0.05). Conclusions Serum IL-6, IL-2 and TNF-α in the process of the development of cerebral infarction play important roles, and their levels can be used in the differential diagnosis of cerebral infarction with acute stage and convalescent stage.

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Available abstract

Objecive to investigate the changes and clinical significance of serum IL-6, IL-2 and TNF-α in patients with acute cerebral infarction. Methods ELISA was applied to measure serum levels of IL-6,IL-2 and TNF-α in 30 cerebral infarction patients at acute stage and at convalescent stage, and the results were compared with those in 32 healthy controls. Results Serum levels of IL-6,IL-2 and TNF-α in the patients were significantly highter than that in the controls(P0.01), the levels in acute stage were highter than that in convalescent stage(P0.05). Conclusions Serum IL-6, IL-2 and TNF-α in the process of the development of cerebral infarction play important roles, and their levels can be used in the differential diagnosis of cerebral infarction with acute stage and convalescent stage.

Key concepts: Medicine, Clinical significance, Cerebral infarction, Stage (stratigraphy), Tumor necrosis factor alpha, Internal medicine, Interleukin 6, Infarction

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Clinical significance of IL-6, IL-2 and TNF-αdetections in patients with cerebral infarction — Research Paper | ScholarLens