Chemical constituents of Lobelia chinensis

Objective To study the chemical constituents in Lobelia chinensis.Methods Isolation and purification were carried out by silica gel,Sephadex LH-20,and preparative HPLC.Their structures were elucidated by spectroscopy and physicochemical properties. Results Twelve compounds were obtained and identified as: cycloeucalenol(Ⅰ),24-methylenecycloartanol(Ⅱ),phytol(Ⅲ),phytenal(Ⅳ),β-amyrin(Ⅴ),adenosine(Ⅵ),n-butyl-β-Dfructofuranoside(Ⅶ),n-butyl-α-D-fructofuranoside(Ⅷ),n-butyl-β-D-fructopyranoside(Ⅸ),n-butyl-α-D-fructopyranoside(Ⅹ),salicin(Ⅺ),and 5-hydroxymethyl furaldehyde(ⅩⅡ).Conclusion Compounds Ⅰ—Ⅳ and Ⅵ—ⅩⅡ are obtained from the plants of Lobelia L.for the first time and compound Ⅴ is obtained from this plant for the first time.