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[Chemical constituents of Lobelia chinensis].

Jinglan Han, Fengling Zhang, Zhihong Li, Guanhua Du, Hailin Qin

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Abstract

OBJECTIVE: To study the chemical constituents from Lobelia chinensis. METHOD: The constituents were extracted with 95% EtOH, partitioned with different solvents, and isolated and purified by silica gel column chromatography and crystallization, their structures were elucidated by physico-chemical properties and spectroscopic data. RESULT: Seven compounds were isolated from the titled plant. They were identified as 5-hydroxy-4'-methoxyflavone-7-O-rutinoside (1), n-butyl-O-beta-D-fructopyranoside (2), 5,7-dimethoxycoumarin (3), cirsiumaldehyde (4), diosmetin (5), 5-hydroxymethyl-2-furancarboxaldehyde (6), and 6-hydroxy-7-methoxycoumarin (7). CONCLUSION: Compounds 2-4, 6, and 7 were obtained from the titled plant for the first time.

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What this paper is about

OBJECTIVE: To study the chemical constituents from Lobelia chinensis. METHOD: The constituents were extracted with 95% EtOH, partitioned with different solvents, and isolated and purified by silica gel column chromatography and crystallization, their structures were elucidated by physico-chemical properties and spectroscopic data. RESULT: Seven compounds were isolated from the titled plant. They were identified as 5-hydroxy-4'-methoxyflavone-7-O-rutinoside (1), n-butyl-O-beta-D-fructopyranoside (2), 5,7-dimethoxycoumarin (3), cirsiumaldehyde (4), diosmetin (5), 5-hydroxymethyl-2-furancarboxaldehyde (6), and 6-hydroxy-7-methoxycoumarin (7). CONCLUSION: Compounds 2-4, 6, and 7 were obtained from the titled plant for the first time.

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Available abstract

OBJECTIVE: To study the chemical constituents from Lobelia chinensis. METHOD: The constituents were extracted with 95% EtOH, partitioned with different solvents, and isolated and purified by silica gel column chromatography and crystallization, their structures were elucidated by physico-chemical properties and spectroscopic data. RESULT: Seven compounds were isolated from the titled plant. They were identified as 5-hydroxy-4'-methoxyflavone-7-O-rutinoside (1), n-butyl-O-beta-D-fructopyranoside (2), 5,7-dimethoxycoumarin (3), cirsiumaldehyde (4), diosmetin (5), 5-hydroxymethyl-2-furancarboxaldehyde (6), and 6-hydroxy-7-methoxycoumarin (7). CONCLUSION: Compounds 2-4, 6, and 7 were obtained from the titled plant for the first time.

Key concepts: Chemical constituents, Silica gel, Chemistry, Chromatography, Hydroxymethyl, Column chromatography, Campanulaceae, Organic chemistry

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