2010•PubMedRequires access

[Studies on the chemical constituents from Lobelia chinensis].

Jianxin Chen, Shen-Hui Huang, Ying Wang, Meng Shao, Wen‐Cai Ye

Abstract

OBJECTIVE: To study the chemical constituents of the full plant of Lobelia chinensis. METHODS: The compounds were isolated and purified using several column chromatographic methods. Their structures were elucidated based on their physicochemical properties and spectral data. RESULTS: Twelve compounds were isolated from L. chinensis. Their structures were elucidated as 6,7-dimethoxycoumarin (1), fraxinol (2), 5-hydroxy-7-methoxycoumarin (3), tomentin (4), 3'-hydroxygenkwanin (5), apigenin (6), quercetin (7), luteolin (8), linarin (9), luteolin 3',4'-dimethylether-7-O-beta-D-glucoside (10), isoferulic acid (11), and ethyl ros-marinate (12), respectively. CONCLUSION: Compounds 1 -5 and 10 -12 are isolated from this plant for the first time.

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Key concepts: Luteolin, Apigenin, Chemistry, Quercetin, Chemical constituents, Spectral analysis, Chemical structure, Column chromatography