2007•Journal of Shantou University Medical CollegeRequires access

Clinical Effect of Naloxone Given to Postoperative Patients with Hypertensive Intracerebral Hemorrhage

Xiaoxuan Fan

Abstract

Objective: To study the clinical effect of naloxone given to postperative patients with hypertensive intracerebral hemorrhage.Methods: The patients were divided into the naloxone group(22 cases)and control group(22 cases)at random.The Glasgow Coma Scale(GCS),Glasgow Outcom Scale(GOS)and the language and movement function scores between two groups were compared.Results: The GCS in the naloxone group was higher than that in the control group at day 7,10(P0.05).After follow-up for 6 months,the GOS and the language function score in the naloxone group were better than those in the control group(P0.05).Conclusion: Large dose of naloxone can effectively protect the cerebral nervous system,and improve the recovery of cerebral nervous system.

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Key concepts: Glasgow Coma Scale, (+)-Naloxone, Medicine, Intracerebral hemorrhage, Anesthesia, Coma (optics), Internal medicine, Opioid