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2007•Journal of Southeast UniversityRequires access

Amniotic fluid cells culture for prenatal genetics diagnois:an analysis of 177 cases

Lizhou Sun

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Abstract

Objective To prevent the birth of fetuses with chromosomal diseases.Method Prenatal diagnoses were performed on 177 women with midtrimester pregnancy.G banding technique was used on cultured amniotic fluid cells.Result In the total 177 cases,167 cases had normal karyotypes,6 cases 21 trisomy,1 case 45,X,3 cases were balanced translocation.The diagnostic results were coincident with the follow up inquiry.Conclusion Amniotic fluid culture for prenatal diagnosis is very safe and reliable.

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Objective To prevent the birth of fetuses with chromosomal diseases.Method Prenatal diagnoses were performed on 177 women with midtrimester pregnancy.G banding technique was used on cultured amniotic fluid cells.Result In the total 177 cases,167 cases had normal karyotypes,6 cases 21 trisomy,1 case 45,X,3 cases were balanced translocation.The diagnostic results were coincident with the follow up inquiry.Conclusion Amniotic fluid culture for prenatal diagnosis is very safe and reliable.

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Available abstract

Objective To prevent the birth of fetuses with chromosomal diseases.Method Prenatal diagnoses were performed on 177 women with midtrimester pregnancy.G banding technique was used on cultured amniotic fluid cells.Result In the total 177 cases,167 cases had normal karyotypes,6 cases 21 trisomy,1 case 45,X,3 cases were balanced translocation.The diagnostic results were coincident with the follow up inquiry.Conclusion Amniotic fluid culture for prenatal diagnosis is very safe and reliable.

Key concepts: Prenatal diagnosis, Amniotic fluid, Trisomy, Obstetrics, Karyotype, Chromosomal translocation, Medicine, Pregnancy

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