Study on Extraction Process of Total Alkaloids in Mulberry Seed with Orthogonal Design

Objective:Mulberry seeds to determine optimal extraction of total alkaloids.Method:Mulberry seeds will be crushed seeds with hexane to skim on Mulberry.Extraction of total alkaloids in mulberry seeds index was investigated concentration of hydrochloric acid,ethanol concentration,extraction time,solvent times the volume,extraction temperature,extraction times on extraction rate of total alkaloids from mulberry seeds the impact of selected leaching temperature,alcohol concentration,hydrochloric acid concentration in the orthogonal design process optimization,the mulberry seeds to determine optimal extraction of total alkaloids.Result:On the extraction rate of primary and secondary order:hydrochloric acid,ethanol concentration,extraction temperature.Best extraction of total alkaloids extracted as:hydrochloric acid concentration of 0.05 mo1L-1,50% ethanol concentration,extraction temperate.Conclusion:The optimum extraction process is achieved,which is stable,feasible,energy-saving,short production cycle,high extraction efficiency,suitable for industrialization.