Effect of Massive Apheresis on Blood Clotting Function for 16 Patients Undergoing Surgery

Objective To summarize the reasonable application in massive transfusion by apheresis in order to improve the clinical transfusion safety.Methods A retrospective analysis was performed on clinical data of 16 patients with massive transfusion(5000 ml) during operations during January 2011 and December 2011,the blood coltting function was detected,and the dosage and species of blood transfusion before and after a blood transfusion were counted.Results The blood clotting of 13 cases in 16 cases were normal before operation.3 cases were abnormal due to liver dysfunction.Blood transfusion average of intraoperative and postoperation were(6404.38±1973.60) ml.The erythrocyte suspension average was(17.75± 6.95) units,refrigerated plasma average was(25.63 ±7.67) units,blood platelets average was(1.31± 1.25) units.8 h after transfusion,the prothrombin time and activated partial thromboplastin time of 16 cases were prolonged and the fibrinogen,blood platetets of 16 cases decreased when compared with that before blood transfusion,the results had statistical significance(P 0.05).Conclusion Patients may suffer from blood clotting functional disorder in massive transfusion,and physicians should be careful in choosing blood composition according to pathogenetic condition and the results of laboratory examinton,in order to reduce adverse rections and improve safety of surgical safety.