Relationship between Carotid Atherosclerotic Plaque and Plasma Fibrinogen

[Objective]To study the relationship between carotid atherosclerosis and plasma fibrinogen.[Methods]Color Doppler was carried out on carotid artery of 65 carotid atherosclerotic patients,recording position,echo intensity of artherosclerotic plaque,carotid artery intima-media thickness and vessel inside diameter.According to carotid artery stenosis,the patients were divided into 4 groups,and were re-divided into 2 groups(hard plaque and soft plaque) on the basis of character of atherosclerotic plaque,meanwhile,detecting the level of plasma fibrinogen,and performing statistical analysis.[Results]With the increasing level of plasma fibrinogen,the degree of carotid atherosclerotic stenosis was increased,showing positive correlation;the rate of plasma fibrinogen soft plaque of middle and high density groups is obviously higher than the lower density group.[Conclusion]Plasma fibrinogen level is closely correlated with characteristic of carotid atherosclerotic plaque.Plasma fibrinogen may determine the stability of carotid atherosclerotic plaque.And the increasing level of plasma fibrinogen is closely related with carotid atherosclerosis and plays an important role in its development.