Clinical Significance of the Platelet Parameters and Changes in Blood Clotting for Patients with Cirrhosis

Objective To investigate clinical significance of the platelet parameters and changes in blood clotting for patients with cirrhosis.Methods Detected 54 cases of liver cirrhosis and 38 healthy subjects by AMAX-200 automatic coagulation analyzer and the Sysmex xs-800i automatic hematology analyzer.Results In patients with cirrhosis,the platelet parameters,platelet count(PLT),average platelet body(MPV),platelet volume distribution width(PDW) were decreased,with the control group comparison there are significant differences(P0.01),platelet hematocrit(PCT) is significantly increased,with the control group comparison there are significant difference(P0.01),blood clotting in the PT,APTT and TT obviously time extension,the FIB was significantly reduced with the healthy control group,there are significant differences(P0.01).Conclusion Platelet parameters and the detection of blood clotting in patients with cirrhosis,early detection of the obstacle of the clotting mechanism,contribute to the disease prognosis and treatment of patients with cirrhosis has important clinical significance in clinical.