Study on Preparative Technique for Qingfeiyihuo Dropping Pills
Wenzhong Wang
Abstract
Wenzhong Wang
Abstract
Objective To optimize the preparative technique of Qingfeiyihuo Dropping Pills.Methods Based on the appearance,variation coefficient of weight of pills,time limit of dissolution of the dropping pills,the proper proportion between the extracts and matrix,dripping temperature,the ratio of matrix,as well as the distance of drops were studied by the orthogonal test.Results The optimum condition was as follows: ratio between extracts and matrix was 1:1,the dripping temperature was 80 ℃,the ratio between PEG4000 and PEG6000 was 2:1,and the dropping distance was 8 cm.Conclusion The preparative technique was convenient,reasonable and feasible.The appearance was good,and the variation coefficient of weight of pills and time limit of dissolution of the dropping pills met the reguirements.
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Objective To optimize the preparative technique of Qingfeiyihuo Dropping Pills.Methods Based on the appearance,variation coefficient of weight of pills,time limit of dissolution of the dropping pills,the proper proportion between the extracts and matrix,dripping temperature,the ratio of matrix,as well as the distance of drops were studied by the orthogonal test.Results The optimum condition was as follows: ratio between extracts and matrix was 1:1,the dripping temperature was 80 ℃,the ratio between PEG4000 and PEG6000 was 2:1,and the dropping distance was 8 cm.Conclusion The preparative technique was convenient,reasonable and feasible.The appearance was good,and the variation coefficient of weight of pills and time limit of dissolution of the dropping pills met the reguirements.
Key concepts: Dissolution, Pill, Coefficient of variation, Matrix (chemical analysis), Chromatography, Mathematics, Chemistry, Analytical Chemistry (journal)