Observation of the effect of montelukast on bronchial asthma

Objective To assess the clinical effect of montelukast on bronchial asthma.Methods 64 cases with mild to moderate bronchial asthma were randomly divided into 2 groups,32 cases per group.Montelukast was given(oral dosage,10mg,once a day) in curative group.Inhaled corticosteroid budesonide was given(400μg per day) in control group.Both groups were given daily inhaled salbutamol,3 to 4 times a day,and the entire observation period for 5 days.And then to observe the two groups of patients with dyspnea,cough,wheezing,wheezing sound condition evaluation,the time of the symptoms disappeared,and the efficiency of treatment.And these indexes were compared in two groups.Results There was no significant difference in clinical symptoms and the time of improvment between the curative group with montelukast and the control group with budesonide(P0.05).Conclusion Montelukast could improve mild to moderate asthma in patients with dyspnea,cough,wheezing symptoms,lung function.It is a new type of anti-inflammatory and anti-asthmatic drugs on bronchial asthma,with a good clinical value.