Distribution and drug resistance of 958 pathogenic strains

OBJECTIVE To understand the clinical hospital distribution of common pathogens and drug resistance,to provide a scientific basis for the rational use of antimicrobial drugs.METHODS From 2008 to 2009,the clinical types of pathogens were isolated,the drug sensitivity test with the KB method in vitro,and a special drug-resistant strains such as methicillin-resistant Staphylococcus(MRS),extended spectrum β-lactam enzymes(ESBLs) were detected.RESULTS The isolation rates of the top five results of the pathogen followed by Escherichia coli(24.6%),Pseudomonas aeruginosa(13.8%),coagulase-negative staphylococci(8.8%),Staphylococcus aureus(7.3%) Klebsiella pneumoniae(6.7%).The detection rates of ESBLs-producing E.coli and K.pneumoniae were 37.7% and 31.3%.The sensitive rate of the isolated Gram-negative bacteria to was 6.8%,to piperacillin/cilostazol pakistan Tanzania,cefepime and amikacin was 20.0%;The detection rates of methicillin-resistant S.aureus and methicillin-resistant coagulase-negative staphylococci were 45.7% and 50%,respectively;Vancomycin-resistant Staphylococcus and Enterococcus were not detected.CONCLUSIONS The clinical isolates are sensitive to imipenem and vancomycin,but the drug resistance to first-line antibiotics in clinic is high and keeps increasing trend.The monitoring to the bacterial resistance in two-star hospital should be strengthened to reduce the spread of drug resistant strains.