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2005•Unpublished venueRequires access

Effect of Meropenem on Ventilator-associated Pneumonia

Ying Zhang

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Abstract

OBJECTIVE To compare the effect and safety between meropenem and imipenem.METHODS A(randomized) comparative study was conducted to compare the clinical effect and safety of meropenem versus(imipenem) in the treatment of 60 cases of ventilator-associated pneumonia.RESULTS Thirty patients of ventilator-associated pneumonia were enrolled into meropenem group with an effective rate of 90.0% and bacteriological(eradication) rate of 83.3%.On the other hand,thirty patients of ventilator-associated pneumonia were enrolled(into) imipenem group with an effective rate of 86.7% and bacteriological eradication rate of 82.1%.There was no significant difference between two groups.The rate of adverse reaction for both meropenem and imipenem was(6.7%.) CONCLUSIONS Meropenem is safe and effective to ventilator-associated pneumonia.

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What this paper is about

OBJECTIVE To compare the effect and safety between meropenem and imipenem.METHODS A(randomized) comparative study was conducted to compare the clinical effect and safety of meropenem versus(imipenem) in the treatment of 60 cases of ventilator-associated pneumonia.RESULTS Thirty patients of ventilator-associated pneumonia were enrolled into meropenem group with an effective rate of 90.0% and bacteriological(eradication) rate of 83.3%.On the other hand,thirty patients of ventilator-associated pneumonia were enrolled(into) imipenem group with an effective rate of 86.7% and bacteriological eradication rate of 82.1%.There was no significant difference between two groups.The rate of adverse reaction for both meropenem and imipenem was(6.7%.) CONCLUSIONS Meropenem is safe and effective to ventilator-associated pneumonia.

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Available abstract

OBJECTIVE To compare the effect and safety between meropenem and imipenem.METHODS A(randomized) comparative study was conducted to compare the clinical effect and safety of meropenem versus(imipenem) in the treatment of 60 cases of ventilator-associated pneumonia.RESULTS Thirty patients of ventilator-associated pneumonia were enrolled into meropenem group with an effective rate of 90.0% and bacteriological(eradication) rate of 83.3%.On the other hand,thirty patients of ventilator-associated pneumonia were enrolled(into) imipenem group with an effective rate of 86.7% and bacteriological eradication rate of 82.1%.There was no significant difference between two groups.The rate of adverse reaction for both meropenem and imipenem was(6.7%.) CONCLUSIONS Meropenem is safe and effective to ventilator-associated pneumonia.

Key concepts: Meropenem, Imipenem, Medicine, Ventilator-associated pneumonia, Pneumonia, Internal medicine, Adverse effect, Antibiotics

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