Effect between Meropenem and Imipenem on Lower Respiratory Tract Infection: A Comparative Study
Rui Wang
Abstract
Rui Wang
Abstract
OBJECTIVE To compare the effect and safety between meropenem and imipenem. METHODS A randomized comparative study was conducted to compare the efficacy and safety of meropenem versus imipenem in the treatment of 76 cases of moderate to severe lower respiratory tract infection. RESULTS Thirty nine patients of lower respiratory tract infection were enrolled into meropenem group with an effective rate of 92.11% and bacteriological eradication rate of 86.11%. On the other hand, 38 patients were enrolled into imipenem group with an effective rate of 92.11% and bacteriological eradication rate of 80.65%. There was not significant difference between two groups.CONCLUSIONS Meropenem is effective to lower respiratory tract infection caused by common bacteria.
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OBJECTIVE To compare the effect and safety between meropenem and imipenem. METHODS A randomized comparative study was conducted to compare the efficacy and safety of meropenem versus imipenem in the treatment of 76 cases of moderate to severe lower respiratory tract infection. RESULTS Thirty nine patients of lower respiratory tract infection were enrolled into meropenem group with an effective rate of 92.11% and bacteriological eradication rate of 86.11%. On the other hand, 38 patients were enrolled into imipenem group with an effective rate of 92.11% and bacteriological eradication rate of 80.65%. There was not significant difference between two groups.CONCLUSIONS Meropenem is effective to lower respiratory tract infection caused by common bacteria.
Key concepts: Meropenem, Imipenem, Medicine, Internal medicine, Lower respiratory tract infection, Respiratory tract infections, Respiratory tract, Antibiotics