ScholarLens Back to search
2008•The Chinese Journal of Modern Applied PharmacyRequires access

Clinical Effect of Ertapenem on Ventilator-associated Pneumonia

Hongyun Zhu

Open publisher page 0 citations

Abstract

OBJECTIVE To compare the effect and safety between ertapenem and imipenem on the ventilator-associated pneumonia. METHODS Trabant comparative study was conducted to compare the clinical effect and safety of ertapenem versus imipenem in the treatment of 60 cases of ventilator-associated pneumonia. RESULTS Thirty patients of ventilator-associated pneumonia were enrolled into ertapenem group with an effective rate of 90.0% and bacteriological eradication rate of 83. 3%. On the other hand, thirty patients of ventilator-associated pneumonia were enrolled into imipenem group with an effective rate of 86.7% and bacteriological eradication rate of 82.1%. There was no significant difference between two groups. The rate of adverse reaction for both ertapenem and imipenem was 6.7%. CONCLUSION Ertapenem is safe and effective to ventilator-associated pneumonia.

About this research paper

What this paper is about

OBJECTIVE To compare the effect and safety between ertapenem and imipenem on the ventilator-associated pneumonia. METHODS Trabant comparative study was conducted to compare the clinical effect and safety of ertapenem versus imipenem in the treatment of 60 cases of ventilator-associated pneumonia. RESULTS Thirty patients of ventilator-associated pneumonia were enrolled into ertapenem group with an effective rate of 90.0% and bacteriological eradication rate of 83. 3%. On the other hand, thirty patients of ventilator-associated pneumonia were enrolled into imipenem group with an effective rate of 86.7% and bacteriological eradication rate of 82.1%. There was no significant difference between two groups. The rate of adverse reaction for both ertapenem and imipenem was 6.7%. CONCLUSION Ertapenem is safe and effective to ventilator-associated pneumonia.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

OBJECTIVE To compare the effect and safety between ertapenem and imipenem on the ventilator-associated pneumonia. METHODS Trabant comparative study was conducted to compare the clinical effect and safety of ertapenem versus imipenem in the treatment of 60 cases of ventilator-associated pneumonia. RESULTS Thirty patients of ventilator-associated pneumonia were enrolled into ertapenem group with an effective rate of 90.0% and bacteriological eradication rate of 83. 3%. On the other hand, thirty patients of ventilator-associated pneumonia were enrolled into imipenem group with an effective rate of 86.7% and bacteriological eradication rate of 82.1%. There was no significant difference between two groups. The rate of adverse reaction for both ertapenem and imipenem was 6.7%. CONCLUSION Ertapenem is safe and effective to ventilator-associated pneumonia.

Key concepts: Ertapenem, Imipenem, Medicine, Ventilator-associated pneumonia, Pneumonia, Carbapenem, Internal medicine, Antibiotics

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Clinical Effect of Ertapenem on Ventilator-associated Pneumonia — Research Paper | ScholarLens