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Study on Quality Standard for Weichangkang Capsules

Wang Qiu-lan

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Abstract

Objective To establish the quality standard for weichangkang capsules. Methods Radix Puerariae in this medicine were identified by TLC. The total contents of magnolol and honokiol were determined by HPLC. Results The qualitative identification with TLC was specific. The methodological study showed a good linear relationship at rang of 0.094 9-1.423 2 μg, 0.040 2～0.602 4 μg. The average recover of magnolol was 101.18% (RSD=1.08%), the average recover of honokiol was 100.47% (RSD=1.89%). Conclusion The methods are simple rapid accurate and reliable, and can be used for quality control of weichangkang capsules.

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What this paper is about

Objective To establish the quality standard for weichangkang capsules. Methods Radix Puerariae in this medicine were identified by TLC. The total contents of magnolol and honokiol were determined by HPLC. Results The qualitative identification with TLC was specific. The methodological study showed a good linear relationship at rang of 0.094 9-1.423 2 μg, 0.040 2～0.602 4 μg. The average recover of magnolol was 101.18% (RSD=1.08%), the average recover of honokiol was 100.47% (RSD=1.89%). Conclusion The methods are simple rapid accurate and reliable, and can be used for quality control of weichangkang capsules.

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Available abstract

Objective To establish the quality standard for weichangkang capsules. Methods Radix Puerariae in this medicine were identified by TLC. The total contents of magnolol and honokiol were determined by HPLC. Results The qualitative identification with TLC was specific. The methodological study showed a good linear relationship at rang of 0.094 9-1.423 2 μg, 0.040 2～0.602 4 μg. The average recover of magnolol was 101.18% (RSD=1.08%), the average recover of honokiol was 100.47% (RSD=1.89%). Conclusion The methods are simple rapid accurate and reliable, and can be used for quality control of weichangkang capsules.

Key concepts: Magnolol, Honokiol, Quality standard, Radix (gastropod), Chromatography, Linear relationship, Chemistry, Mathematics

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