A Study on the Relationship between Serum Uric Acid and the Related Risk Factors of Cardiovascular Diseases

Objective To explore the relationship between serum uric acid and the related risk factors of cardiovascular diseases.Methods The blood samples were collected from 380 individuals who were performing health examination including the measurement of the body heights,weights,body mass index(BMI) ,systolic blood pressure(SBP) ,diastolic blood pressure(DBP) ,at the same time,measured serum uric acid(SUA) ,the fasting blood glucose(FBG) ,serum triglyceride(TG) ,serum total cholesterol(TC) ,serum high density lipoprotein cholesterol(HDLCH) ,serum low density lipoproteincholesterol(LDLCH) ,and 2-hour postprandial blood glucose(2hPG) of oral glucose tolerance tests as well as biochemistry targets from August to September 2007 in our hospital.Results The prevalence of hyperuricemia peoples in this group was 47.1%.Hyperuricemia peoples had high body mass index(BMI) ,high TG,hypertension,and low HDLCH,showing significant differences(P0.01) when compared with those without hyperuricemia.The results of linear correlation analysis revealed that serum uric acid concentration was in a positive correlation with BMI,serum TG,SBP,and DBP,while in a negative correlation with HDLCH(P0.001) .Partial correlation analysis showed that serum uric acid concentration was also in a positive correlation with BMI and DBP except other effective factors(P0.001) .Conclusion Hyperuricemia was an independent risk factor of obesity and hypertension.