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2003•Journal of Huaihai MedicineRequires access

Clinical significance of conbined detection of serum TNF-α、IL-6 and IL-8 in patients with hepatitis C

Zhang Yun-ya

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Abstract

Objective To explore the changes of serum TNF-α?IL-6?IL-8 levels in patients wiht hepatitis C.Methods Levels of serum TNF-α was detected by RIA,IL-6 and IL-8 by ELISA in 58 cases of hepatitis C and 35 normal controls.Results Serum levels of TNF-α?IL-6 and IL-8 were higher than those in normal controls(P 0.01),There were positive correlation between serum levels of TNF-α,IL-6 and IL-8 and serum ALT and total bilirubin.Conclusion Serum levels of TNF-α,IL-6 and IL-8 in patients with hepatitis C are related to immune function injury degree of liver.

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What this paper is about

Objective To explore the changes of serum TNF-α?IL-6?IL-8 levels in patients wiht hepatitis C.Methods Levels of serum TNF-α was detected by RIA,IL-6 and IL-8 by ELISA in 58 cases of hepatitis C and 35 normal controls.Results Serum levels of TNF-α?IL-6 and IL-8 were higher than those in normal controls(P 0.01),There were positive correlation between serum levels of TNF-α,IL-6 and IL-8 and serum ALT and total bilirubin.Conclusion Serum levels of TNF-α,IL-6 and IL-8 in patients with hepatitis C are related to immune function injury degree of liver.

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Available abstract

Objective To explore the changes of serum TNF-α?IL-6?IL-8 levels in patients wiht hepatitis C.Methods Levels of serum TNF-α was detected by RIA,IL-6 and IL-8 by ELISA in 58 cases of hepatitis C and 35 normal controls.Results Serum levels of TNF-α?IL-6 and IL-8 were higher than those in normal controls(P 0.01),There were positive correlation between serum levels of TNF-α,IL-6 and IL-8 and serum ALT and total bilirubin.Conclusion Serum levels of TNF-α,IL-6 and IL-8 in patients with hepatitis C are related to immune function injury degree of liver.

Key concepts: Medicine, Serum bilirubin, Hepatitis, Clinical significance, Tumor necrosis factor alpha, Immunology, Immune system, Bilirubin

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Clinical significance of conbined detection of serum TNF-α、IL-6 and IL-8 in patients with hepatitis C — Research Paper | ScholarLens