2009•Xiandai shengwu yixue jinzhanRequires access

Analysis of 217 Cases of Adverse Drug Reactions

Rui Wang, Wu PeiFen

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Abstract

Objective: To study the characteristics of ADR occurred in our hospital and to promote rational clinical drug use. Methods: A total of 217 ADR reports were collected and statistically analyzed in respect of age and sex of patients, route of administration, ADR degree, drug category, ADR-involving organs and clinical manifestations etc. Results: ADR-involving drugs totaled 217 kinds, of which anti-infective agents occupied the first place, followed by Chinese patent medicines. 151 ADRcases (69.59%) were induced by intravenous route. ADR occurred systemically and were characterized predominantly by allergic reactions of skin and its appendants, lesions of skin and its appendages accounted for 67.74% of the total ADR cases. Conclusion: Importance should be attached to the reporting and monitoring of ADR so as to lessen or avoid the occurrence of ADR in the clinic.

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What this paper is about

Objective: To study the characteristics of ADR occurred in our hospital and to promote rational clinical drug use. Methods: A total of 217 ADR reports were collected and statistically analyzed in respect of age and sex of patients, route of administration, ADR degree, drug category, ADR-involving organs and clinical manifestations etc. Results: ADR-involving drugs totaled 217 kinds, of which anti-infective agents occupied the first place, followed by Chinese patent medicines. 151 ADRcases (69.59%) were induced by intravenous route. ADR occurred systemically and were characterized predominantly by allergic reactions of skin and its appendants, lesions of skin and its appendages accounted for 67.74% of the total ADR cases. Conclusion: Importance should be attached to the reporting and monitoring of ADR so as to lessen or avoid the occurrence of ADR in the clinic.

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Available abstract

Objective: To study the characteristics of ADR occurred in our hospital and to promote rational clinical drug use. Methods: A total of 217 ADR reports were collected and statistically analyzed in respect of age and sex of patients, route of administration, ADR degree, drug category, ADR-involving organs and clinical manifestations etc. Results: ADR-involving drugs totaled 217 kinds, of which anti-infective agents occupied the first place, followed by Chinese patent medicines. 151 ADRcases (69.59%) were induced by intravenous route. ADR occurred systemically and were characterized predominantly by allergic reactions of skin and its appendants, lesions of skin and its appendages accounted for 67.74% of the total ADR cases. Conclusion: Importance should be attached to the reporting and monitoring of ADR so as to lessen or avoid the occurrence of ADR in the clinic.

Key concepts: Medicine, Drug, Drug reaction, Intravenous route, Adverse drug reaction, Route of administration, Pharmacology, Dermatology

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