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2009•Anhui Medical and Pharmaceutical JournalRequires access

Analysis of 262 cases of adverse drug reactions reported

WU Pei-fen

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Abstract

Aim To study the characteristics of ADR occurred in our hospital and to promote rational clinical drug use.Method A total of 262ADR reports were collected and statistically analyzed in respect of age and sex of patients,route of administration,ADR degree,drug category,ADR-involving organs and clinical manifestations etc.Results ADR-involving drugs totaled 262 kinds,of which anti-infective agents occupied the first place,followed by Chinese patent medicines.172 ADR cases(65.65%) were induced by intravenous route.ADR occurred systemically and were characterized predominantly by allergic reactions of skin and its appendants,lesions of skin and its appendages accounted for 69.85% of the total ADR cases.Conclusion Importance should be attached to the reporting and monitoring of ADR so as to lessen or avoid the occurrence of ADR in the clinic.

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Aim To study the characteristics of ADR occurred in our hospital and to promote rational clinical drug use.Method A total of 262ADR reports were collected and statistically analyzed in respect of age and sex of patients,route of administration,ADR degree,drug category,ADR-involving organs and clinical manifestations etc.Results ADR-involving drugs totaled 262 kinds,of which anti-infective agents occupied the first place,followed by Chinese patent medicines.172 ADR cases(65.65%) were induced by intravenous route.ADR occurred systemically and were characterized predominantly by allergic reactions of skin and its appendants,lesions of skin and its appendages accounted for 69.85% of the total ADR cases.Conclusion Importance should be attached to the reporting and monitoring of ADR so as to lessen or avoid the occurrence of ADR in the clinic.

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Available abstract

Aim To study the characteristics of ADR occurred in our hospital and to promote rational clinical drug use.Method A total of 262ADR reports were collected and statistically analyzed in respect of age and sex of patients,route of administration,ADR degree,drug category,ADR-involving organs and clinical manifestations etc.Results ADR-involving drugs totaled 262 kinds,of which anti-infective agents occupied the first place,followed by Chinese patent medicines.172 ADR cases(65.65%) were induced by intravenous route.ADR occurred systemically and were characterized predominantly by allergic reactions of skin and its appendants,lesions of skin and its appendages accounted for 69.85% of the total ADR cases.Conclusion Importance should be attached to the reporting and monitoring of ADR so as to lessen or avoid the occurrence of ADR in the clinic.

Key concepts: Medicine, Drug, Drug reaction, Intravenous route, Adverse drug reaction, Route of administration, Pharmacology, Dermatology

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