CLINICAL PATHOLOGICAL ANALYSIS OF 16 CASES OF SOLITARY FIBROUS TUMORS

[Objective]To explore the clinical morphology and immunohistochemical features of Solitary Fibrous Tumor(SFT).[Methods]Used light microscopy and immunohistochemical staining to analyze 16 cases of SFT.[Results]The 7 male and 9 female patients between 20 and 68 years old(mean 45)were analyzed.SFTS occurred in 9 sites and the main clinical manifestations were local mass and pressure symptom.Histologically,the tumors composed of hypoand hyper cellar areas,Keloid-like Collagen bundles in the stroma,thin-walled branching vessels and Hpc-like growth pattern..For immunohistochemical staining,Vimitin and CD34 positive rate was 100%(16/16),CD99 87%(14/16),SMA 25%(4/16),EMA 19%(3/16),S-100 13%(2/16).[Conclusion]SFT may be found in various parts of human body and needs to be distinguished from other spindle cell tumors by differential diagnosis.The immunophenotype can be helpful.Most SFT is a benign tumor and only a few have local recurrence or metastasis,which need surgical removal as a main cure and regular follow-up is necessary