Clinical and Pathological Analysis of Pulmonary Sclerosing Hemangioma and a Review of Literature
Shijun Li
Abstract
Shijun Li
Abstract
Objective:This study aimed to better understand the clinical features,pathological patterns of pulmonary sclerosing hemangioma.Methods:The clinical data and immunohistology of 4 cases of psh were analyzed,and the literature was reviewed.Results:There were 4 females.HE stiaining revealed that PSH showed a mixture of the following four histological patterns:solid,papillary,hemangioma-like and sclerotic.there were two types of tumor cells:cubodal cells and round cells.immunohistochemical staining revealed that two types cells expressed EMA and TTF-1,the cuboidal cells expressed CK7;on the other hand,round cells expressed PR,none of them expressed syn and CgA.Conclusions:PSH is an uncommon disease,The immunohistochemical markers such as EMA,TTF-1,CK7 are helpful for diagnosis.if it is a a benign tumour with potential for malignancy More attention should be paid to its clinical features and management.
A significance statement is not available in the OpenAlex record.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
Objective:This study aimed to better understand the clinical features,pathological patterns of pulmonary sclerosing hemangioma.Methods:The clinical data and immunohistology of 4 cases of psh were analyzed,and the literature was reviewed.Results:There were 4 females.HE stiaining revealed that PSH showed a mixture of the following four histological patterns:solid,papillary,hemangioma-like and sclerotic.there were two types of tumor cells:cubodal cells and round cells.immunohistochemical staining revealed that two types cells expressed EMA and TTF-1,the cuboidal cells expressed CK7;on the other hand,round cells expressed PR,none of them expressed syn and CgA.Conclusions:PSH is an uncommon disease,The immunohistochemical markers such as EMA,TTF-1,CK7 are helpful for diagnosis.if it is a a benign tumour with potential for malignancy More attention should be paid to its clinical features and management.
Key concepts: Medicine, Pathological, Immunohistochemistry, Malignancy, Pathology, Hemangioma, Staining