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2001•Chinese Journal of New Drugs and Clinical RemediesRequires access

Levofloxacin in treating lower respiratory tract bacterial infection in outpatients with acute exacerbation of chronic obstructive pulmonary disease

Qiu Wang

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Abstract

AIM: To evaluate the efficacy,safety and practicality of levofloxacin tablets in treating lower respiratory tract bacterial infection in patients with acute exacerbation of chronic obstructive pulmonary disease(COPD). METHODS:Thirty COPD outpatients with lower respiratory tract bacterial infection (M 18,F 12;age 56 a± s 10 a) were treated with levofloxacin 200 mg, po , bid for 3 4 d,followed by 100 mg po ,bid for 4～5 d,total treatment course was 7 9 d. RESULTS: The effective rate was 97%,the cure rate was 74% and the bacterial eradication rate was 92%.Adverse reaction were rare and mild.CONCLUSION:Levofloxacin is an effective and safe antibiotic in the treatment of lower respiratory tract infection in outpatients with acute exacerbation of COPD,and the therapeutic course is short.

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What this paper is about

AIM: To evaluate the efficacy,safety and practicality of levofloxacin tablets in treating lower respiratory tract bacterial infection in patients with acute exacerbation of chronic obstructive pulmonary disease(COPD). METHODS:Thirty COPD outpatients with lower respiratory tract bacterial infection (M 18,F 12;age 56 a± s 10 a) were treated with levofloxacin 200 mg, po , bid for 3 4 d,followed by 100 mg po ,bid for 4～5 d,total treatment course was 7 9 d. RESULTS: The effective rate was 97%,the cure rate was 74% and the bacterial eradication rate was 92%.Adverse reaction were rare and mild.CONCLUSION:Levofloxacin is an effective and safe antibiotic in the treatment of lower respiratory tract infection in outpatients with acute exacerbation of COPD,and the therapeutic course is short.

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Available abstract

AIM: To evaluate the efficacy,safety and practicality of levofloxacin tablets in treating lower respiratory tract bacterial infection in patients with acute exacerbation of chronic obstructive pulmonary disease(COPD). METHODS:Thirty COPD outpatients with lower respiratory tract bacterial infection (M 18,F 12;age 56 a± s 10 a) were treated with levofloxacin 200 mg, po , bid for 3 4 d,followed by 100 mg po ,bid for 4～5 d,total treatment course was 7 9 d. RESULTS: The effective rate was 97%,the cure rate was 74% and the bacterial eradication rate was 92%.Adverse reaction were rare and mild.CONCLUSION:Levofloxacin is an effective and safe antibiotic in the treatment of lower respiratory tract infection in outpatients with acute exacerbation of COPD,and the therapeutic course is short.

Key concepts: Levofloxacin, Medicine, Exacerbation, COPD, Respiratory tract, Internal medicine, Antibiotics, Respiratory tract infections

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Levofloxacin in treating lower respiratory tract bacterial infection in outpatients with acute exacerbation of chronic obstructive pulmonary disease — Research Paper | ScholarLens