Comparison of the Contents of Tanshinone IIA and Salvianolic Acid B in Salviae Miltiorrhizae from Different Producing Areas

Objective: To determine and compare the contents of tanshinoneⅡA and salvianolic acid B in salviae miltiorrhizae from different producing areas. Methods: HPLC was employed to determine the contents of tanshinoneⅡA and salvianolic acid B. Synchropak PR100- 5 column was adopted in this process. The detective wavelength was set at 270 nm and 286nm,respectively. Results: Both of tanshinone ⅡA and salvianolic acid B levels of salviae miltiorrhizae from Sichuan Zhongjiang were higher. However,the tanshinone ⅡA level of salviae miltiorrhizae from Shanxi Ruicheng was the lowest,but salvianolic acid B level was the highest. Conclusion: The contents of tanshinoneⅡA and salvianolic acid B in salviae miltiorrhizae could be related to different producing areas. The results can be used as a reference for purchasing and using salviae miltiorrhizae in clinic.