A Clinical Observation on Different Does of Mifepristone for Emergency Contraception

Objective To evaluate the emergency contraceptive efficacy, the side effects and the influence to the next menstruation of two different low does of mifepristone. Methods 200healthy women with regular cycles and history were recruited within 72hours after unprotected intercourse or contraceptivefaiture, and they were randomly allocated into two groups. Group I mifepristone 50mg was given orally and groupII 25mg. Following-up visit was paid to evaluate the contraceptive efficacy and to record its side effects and menstruation. Results The emergency contraceptive effctiveness rate were 89.13%, 88.29% respectively and the side effects were slight and tolerable. The percentage of subjects who had a early onset of menses was 11%, 22% respectively and those who had a late one was 17%, 12% respectively. There was no statistically difference between the two groups. Conclusion Using of the two different low does of mifepristone for emergency contraception is effective and safe.