2007•Zhongyang Minzu Daxue xuebaoRequires access

Effects of Lutein on Antioxidantive Action in Aged Rat

Pei Ling-peng

Abstract

To cause aging,Wistar rats were given injections of D-galactose for 5 months.They were randomly divided in four groups,including model group、low-medication group、middle-medication group and high-medication group whose the content of serum MDA、liver MDA and the activity of SOD and GSH-Px were tested and compared.Experimental results showed that the content of serum MDA、liver MDA in the medication group were significantly decreased(P0.01),compared with model group.However,the activity of SOD and GSH-Px was significantly raised(P0.01).Therefore lutein can increase antioxidantive function of rat to stay D-galactose induced consenescence.

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Key concepts: Lutein, Internal medicine, Malondialdehyde, Endocrinology, Liver function, Normal group, Galactose, Glutathione