2007•Zhongguo laonianxue zazhiRequires access

Effect of Tagetes erecta L.′s extraction on antioxidative function in aged rats

Ling Pei

Abstract

Objective To study the effect of extraction of Tagetes erecta L. on the antioxidative function of D-galactose (D-gal)induced aged rat.Methods Wistar rats had been given D-gal injections for 5 months to make aging model.They were randomly divided in model group,low-dose lutein group,middle-dose lutein group and high-dose lutein group.Then the content of serum MDA,liver MDA and the activity of SOD and GSH-Px were tested and compared with each group.Results Compared with model group,the content of serum MDA,liver MDA in the lutein group were significantly decreased (P0.01).However the activity of SOD and GSH-Px was significantly raised(P0.01).Conclusions Extraction of Tagetes erecta L. can increase antioxidative function of rat and postpone consenescence induced by D-gal.

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Key concepts: Tagetes, Lutein, Extraction (chemistry), Malondialdehyde, Traditional medicine, Chemistry, Glutathione, Antioxidant