2014•Chinese Journal of Hospital PharmacyRequires access

Optimization of the extraction process of polysaccharide in Polygonatum and Fructus Lycii with orthogonal test

LI Juan-jua

Abstract

OBJECTIVE To find out the optiminal extraction process of polysaccharide from Polygonatum and Fructus Lycii. METHODS With total polysaccharides and dry extract rate as the parameters for water-extraction,times of extraction,time and the ratio of material to water were used for the optimization of water-extraction technology.RESULTS The optimum extraction process:water doses was 10,8,8×,reflux extraction for 3 times and 1.5 h,1 h,1 h each time respectively.The extraction rate of soluble polysaccharides was 10.98% in the optimum conditions.CONCLUSION The optimum extraction process is stable and feasible.

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Key concepts: Extraction (chemistry), Polysaccharide, Chromatography, Water extraction, Hot water extraction, Process (computing), Chemistry, Biochemistry