2011•Journal of Medical Pest ControlRequires access

Anti-oxidation effect of grape seed extract complex on mice

Shufen Chen

Abstract

Objective This paper studied the anti-oxidation effect of grape seed extract complex.Method 48 mice were randomly divided into 4 groups,different dose of grape seed extract complex were given to high dose group(1.31g/kg),middle dose group(0.87g/kg) and low dose group(0.44g/kg) through mouth,the blank control group was given same volume solvent.The activity of anti-oxidation enzyme in serum was tested for three doses of groups and blank control group after 45 days of consecutive drug or solvent giving.Results The activity of SOD and GSH-Px in high dose group were significantly higher than that in control group(P0.01).Conclusions The results suggested this complex had some anti-oxidation function.

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Key concepts: Grape seed, Grape seed extract, Chemistry, Positive control, Food science, Enzyme, Biochemistry, Medicine