SOLITARY FIBROUS TUMOR: A REPORT OF TWO CASES

Objective To investigate the clinicopathologic features,diagnosis,and bionomics of solitary fibrous tumor(SFT). Methods Histology and immunohistochemistry of two solitary fibrous tumors were studied and related literature reviewed. Results SFT had its own unique histopathologic structure,showing a great difference in different regions in the same case.The tumor was mainly composed by non-structural hyperplastic short-spindle or oval cells,distributing alternately among cell-cluster and cell-puff zone.Hemangiopericytoma-like structure could be seen,with profuse blood vessels among the cells.Immunohistochemistry showed CD34(+),and CD99(+). Conclusion Solitary fibrous tumor can occur in extrathoracic locations,most manifest a benign course clinically,with 10%-15% of them show atypical or malignant changes.