Analysis of Clinicopathological features in 3 cases with solitary fibrous tumor

Objective: To study the characteristics of clinicopathology and immunohistochemistry stain and diagnosis with its differential diagnosis in solitary fibrous tumor(SFT).Methods: Light microscopy and immunohistochemical stains were performed in 3 cases with solitary fibrous tumor. Their clinical information and some relative literatures were reviewed.Results: The tumor was large in 3 cases of SFT.The tumor composed of spindle fibroblast-like cells and minority orbicular-ovate cells.The spindle cells arranged in short intersecting fascicles or storiform arrays.The part areas showed hemangioma-like structure,and more collagen fiber.The cases 2,3 were benign tumors.Cases 1 occurred in abdominal cavity.Mitoses index was high(4 mitoses per 10 high-power fields) with infiltrative growth pattern.The case was diagnosed invasion SFT.Expression of CD34,bcl-2 and Vim were detected in all cases.Conclusion: SFT is a rare spindle cell tumor.There are located at more organs and tissues and histological diversity.The majority tumor is benign SFT,only a few cases are invasive SFT.