2008China Practical MedicineRequires access

A control study of fluvoxamine and paroxetine in the treatment of obsessive-compulsive disorder

Gong Fei-zhong

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Abstract

Objective To compare the efficacy and side effects of fluvoxamineine and paroxetine in the treatment of obsessive-compulsive disorder(OCD).Methods 72 patients with OCD were randomly assigned into fluvoxamineine group and paroxetinegroup.The efficacy was measured with Yale-Brown and Hamilton Depression Scale(HAMD).The side effects were deter-mined by the Treatment Emergent Symptom Scale(TESS).Results There was no significant difference in the efficacy between two groups.The side effects of fluvoxamineine were lower than those of paroxetine.Conclusion Fluvoxamineine in the treatment of OCD is effective and safe.

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What this paper is about

Objective To compare the efficacy and side effects of fluvoxamineine and paroxetine in the treatment of obsessive-compulsive disorder(OCD).Methods 72 patients with OCD were randomly assigned into fluvoxamineine group and paroxetinegroup.The efficacy was measured with Yale-Brown and Hamilton Depression Scale(HAMD).The side effects were deter-mined by the Treatment Emergent Symptom Scale(TESS).Results There was no significant difference in the efficacy between two groups.The side effects of fluvoxamineine were lower than those of paroxetine.Conclusion Fluvoxamineine in the treatment of OCD is effective and safe.

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Available abstract

Objective To compare the efficacy and side effects of fluvoxamineine and paroxetine in the treatment of obsessive-compulsive disorder(OCD).Methods 72 patients with OCD were randomly assigned into fluvoxamineine group and paroxetinegroup.The efficacy was measured with Yale-Brown and Hamilton Depression Scale(HAMD).The side effects were deter-mined by the Treatment Emergent Symptom Scale(TESS).Results There was no significant difference in the efficacy between two groups.The side effects of fluvoxamineine were lower than those of paroxetine.Conclusion Fluvoxamineine in the treatment of OCD is effective and safe.

Key concepts: Paroxetine, Hamd, Medicine, Obsessive compulsive, Hamilton depression scale, Fluvoxamine, Depression (economics), Clinical efficacy

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