Comparative study of tiaozhi zengshou tang in treatment of dyslipidaemia

AIM:To observe the clinical curative effect of tiaozhi zengshou tang in patients with dyslipidaemia. METHODS: Ninety three patients with dyslipidaemia were randomized into three groups: 31 patients in traditional Chinese medicine(TCM) group that receiving tiaozhi zengshou tang,30 patients in western medicine group that receiving Mevalotin,and 32 patients in combined treatment group that receiving tiaozhi zengshou tang and Mevalotin. The therapeutic course for each group was 8 weeks. The effect in regulating blood lipids and adverse effect in patients were observed. RESULTS: The total effective rate of the TCM was 81%.Tiacylglycerol (TG) and total cholesterol(TC) in the TCM group were decreased from (2.59±1.64) mmol/L to(1.56±0.72) mmol/L,from (5.3±1.71) mmol/L to (4.35±0.85) mmol/L respectively, which indicated significant difference before and after treatment (t=2.51, 2.77,P 0.05). As compared with western medicine group,there was no significant difference(P 0.05); The level of high density lipoprotein cholesterol was significantly increased from (1.37±0.36) mmol/L to (1.52±0.18) mmol/L in the TCM group, which showed significant difference before and after treatment(t=2.45,P 0.05).The adverse effect of the TCM group occurred less than that of the western medicine group, which showed significant difference (P 0.05). CONCLUSION:Tiaozhi zengshou tang has definite curative effect in patients with dyslipidaemia and has few adverse effects.