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Optimization of Extraction Process for Compound Ganmaoling Capsules by Orthogonal Design

Liu Yan-jun

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Abstract

Objective To study the optimum extraction process of Compound Ganmaoling Capsules by orthogonal design. Methods The rate of extraction and the content of chlorogenic acid were chosen as the assessment indexes.The amount of water, boiling duration and boiling times were studied to examine the extraction process by orthogonal design. Results The optimum water extraction process conditions were adding ten times amount of water for the first time and eight times amount of water for the second time, 1.5 h each time. Conclusion The preparation method is reasonable and stable.

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What this paper is about

Objective To study the optimum extraction process of Compound Ganmaoling Capsules by orthogonal design. Methods The rate of extraction and the content of chlorogenic acid were chosen as the assessment indexes.The amount of water, boiling duration and boiling times were studied to examine the extraction process by orthogonal design. Results The optimum water extraction process conditions were adding ten times amount of water for the first time and eight times amount of water for the second time, 1.5 h each time. Conclusion The preparation method is reasonable and stable.

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Available abstract

Objective To study the optimum extraction process of Compound Ganmaoling Capsules by orthogonal design. Methods The rate of extraction and the content of chlorogenic acid were chosen as the assessment indexes.The amount of water, boiling duration and boiling times were studied to examine the extraction process by orthogonal design. Results The optimum water extraction process conditions were adding ten times amount of water for the first time and eight times amount of water for the second time, 1.5 h each time. Conclusion The preparation method is reasonable and stable.

Key concepts: Boiling, Chlorogenic acid, Extraction (chemistry), Process (computing), Chromatography, Water extraction, Boiling point, Process engineering

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