2009•Chinese Journal of Ethnomedicine and EthnopharmacyRequires access

Experimental study on SOD、GSH-Px、CAT、MDA effects in mice blood of KOTAIS

Huimin Chen

Abstract

OBJECTIVE:To study the anti-aging effects of KOTAIS on model mice by measuring SOD、GSH-Px、CAT、MDA levels of blood.METHODS:Random groups were prepared by weight for 5 groups and were given normal,D-galactose,and the low and middle and high of KOTAIS.Interrelated senile indexes were measured after successively give medicine for 60 days.RESULTS:Every dose group is able to improve the activities of SOD and GSH-Px and CAT and decrease the level of MDA in blood of all mice.The effects of anti-aging is very obviously for middle dose group.CONCLUSION:KOTAIS has anti-aging effects by eliminating free radicals.

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Key concepts: Superoxide dismutase, Chemistry, Normal group, Antioxidant, Body weight, Internal medicine, Endocrinology, Pharmacology