The clinical isolating rate and drug resistance of yeast fungi in Changgang General Hospital from 2004 to 2007

Objective To investigate the infection status of yeast fungi and their drug resistance,and instruct the clinic to use antifungal agents rationally.Methods CHRO Mager monilial coloration culture medium identification and conventionally manual i- dentification method were applied to isolating and identifying 212 strains of yeast fungi;ATB FUNGUS susceptibility test strip was employed to determining the sensitivity of yeast fungi to 6 kind of antifungal agents.Results 212 strains of yeast fungi were detec- ted out of the delivered 444 3 samples from 2004 to 2007.The pharyngeal swab had the highest isolating rate (6.4%),followed by sputum (5.4%) and stool sample (5.3%).The detection rate was gradually rising year by year,from 2.6% in 2004 to 7.3% in 2007.Among the total,Candida albicans were 134 strains (63.2%),and Candida tropicalis were 33 strains (15.6%).The resist- ant rate of 212 strains of yeast fungi were 0%-30% to 5-flucytosine,mycostatin,amphotericin,ketoconazole,miconazole and econ- azole.Conclusion The location of yeast fungus infection focuses on the respiratory tract and intestinal tract,and Candida albicans was a common causative fungus.The sensitivity of yeast fungi was higher to 6 kind of antifungal agents.