The analysis of clinincal distribution and drug resistance of 281 strains of infected fungus

Objective To discuss the normal kinds of yeast-like fungi causing infection and the drug resistance status,and to provide guidance for etiologic diagnosis and suitable anti-fungus management.Methods The fungi were cultured with normal method,then cultured,separated,purified with blood and sabouraud′s culture medium.The bud tube was grown in experimental serum.Then the fungi was isolated and indentified with API-20CAUX indentification system.The antifungal sensitivity was detected with ATB-Fungus trip.Results Totally 16 species were identified from 281 strains of fungus,predominantly Candida abicans(58.4%),C.tropicialis(16.7%),Mucor(4.6%).The isolated fungi were rather sensitive to amphotericin band fluconazole,but drug resistance rate to itraconazole and 5-flucytosine was high.Conclusion Isolation and anti-fungal sensitivity tests should be stressed for clinical microorganism room and clinical selection of reasonable anti-fugals.