The expression of Ki-67 in cancer tissues of patients with renal cell carcinoma

Objective The roles of Ki-67 in the development of renal cell carcinoma were studied by observing it′s expression in cancer tissues.Methods Immunohisto -chemical staining for Ki-67 was performed by streptavidin-biotin method in 20 renal cell carcinoma patients.Results The mean Ki-67 labeling index was significantly increased in cancer tissues of 25.40±9.97% than in adjacent tissues of 11.79 ±4.82 % (P0.01 ).Conclusion The increased expression of Ki-67 values suggested that Ki-67 be correlated to the development of renal cell carcinoma. Ki-67 can be used as a clinical marks in defining tumour behaviour of renal cell carcinoma.