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2004•Journal of Nantong MedicalRequires access

The Changes of Serum Hydroxyproline (Hyp) in Experimental Hepatic Fibrosis in Rats

Yang Daming

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Abstract

Objective:To explore the changes of serum Hyp in experimental hepatic fibrosis in rats.Methods:Experimental models were produced by repeated injections of pig serum,the contents of Hyp were measured after treatment.Result: Serum Hyp were markedly increased in modle groups(P0.05), serum Hyp levels ,hepatic fibrosis degrees were positive corretlated(r=0.805,P0.05).Conclusions:The serum Hyp levels may be an good indicator of hepatic fibrosis.

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Objective:To explore the changes of serum Hyp in experimental hepatic fibrosis in rats.Methods:Experimental models were produced by repeated injections of pig serum,the contents of Hyp were measured after treatment.Result: Serum Hyp were markedly increased in modle groups(P0.05), serum Hyp levels ,hepatic fibrosis degrees were positive corretlated(r=0.805,P0.05).Conclusions:The serum Hyp levels may be an good indicator of hepatic fibrosis.

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Available abstract

Objective:To explore the changes of serum Hyp in experimental hepatic fibrosis in rats.Methods:Experimental models were produced by repeated injections of pig serum,the contents of Hyp were measured after treatment.Result: Serum Hyp were markedly increased in modle groups(P0.05), serum Hyp levels ,hepatic fibrosis degrees were positive corretlated(r=0.805,P0.05).Conclusions:The serum Hyp levels may be an good indicator of hepatic fibrosis.

Key concepts: Hydroxyproline, Hepatic fibrosis, Internal medicine, Endocrinology, Fibrosis, Medicine, Serum concentration, Chemistry

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