ScholarLens Back to search
2009•Acta Academiae Medicinae Qingdao UniversitatisRequires access

THE CHANGES AND CLINICAL SIGNIFICANCE OF ISCHEMIA MODIFIED ALBUMIN AND SOLUBLE INTERCELLULAR ADHESION MOLECULE-1 IN PATIENTS WITH CORONARY HEART DISEASE

W Chen

Open publisher page 0 citations

Abstract

Objective To explore the association of the changes of serum ischemia modified albumin(IMA) and soluble intercellular adhesion molecule-1(sICAM-1) levels with coronary heart disease(CHD). Methods The concentrations of serum IMA and sICAM-1 in 120 CHD patients were determined by ELISA and compared with 40 controls. Results The serum IMA and sICAM-1 in the CHD were higher than those in the controls(t′=18.45,11.02;P0.001).The differences of serum levels of IMA and sICAM-1 among the AMI,UAP and SAP patients were significant(F=102.16,32.81;q=3.70-20.24;P0.001).There was a positive correlation between IMA and sICAM-1 in patients with different-type CHD(r=0.609-0.855,P0.01).Conclusion The changes of serum IMA and sICAM-1 involve in the onset and development of CHD,which is associated with the severity of the disease.

About this research paper

What this paper is about

Objective To explore the association of the changes of serum ischemia modified albumin(IMA) and soluble intercellular adhesion molecule-1(sICAM-1) levels with coronary heart disease(CHD). Methods The concentrations of serum IMA and sICAM-1 in 120 CHD patients were determined by ELISA and compared with 40 controls. Results The serum IMA and sICAM-1 in the CHD were higher than those in the controls(t′=18.45,11.02;P0.001).The differences of serum levels of IMA and sICAM-1 among the AMI,UAP and SAP patients were significant(F=102.16,32.81;q=3.70-20.24;P0.001).There was a positive correlation between IMA and sICAM-1 in patients with different-type CHD(r=0.609-0.855,P0.01).Conclusion The changes of serum IMA and sICAM-1 involve in the onset and development of CHD,which is associated with the severity of the disease.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To explore the association of the changes of serum ischemia modified albumin(IMA) and soluble intercellular adhesion molecule-1(sICAM-1) levels with coronary heart disease(CHD). Methods The concentrations of serum IMA and sICAM-1 in 120 CHD patients were determined by ELISA and compared with 40 controls. Results The serum IMA and sICAM-1 in the CHD were higher than those in the controls(t′=18.45,11.02;P0.001).The differences of serum levels of IMA and sICAM-1 among the AMI,UAP and SAP patients were significant(F=102.16,32.81;q=3.70-20.24;P0.001).There was a positive correlation between IMA and sICAM-1 in patients with different-type CHD(r=0.609-0.855,P0.01).Conclusion The changes of serum IMA and sICAM-1 involve in the onset and development of CHD,which is associated with the severity of the disease.

Key concepts: Ischemia-modified albumin, Medicine, Internal medicine, Coronary heart disease, Albumin, Intercellular Adhesion Molecule-1, Clinical significance, Serum albumin

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
THE CHANGES AND CLINICAL SIGNIFICANCE OF ISCHEMIA MODIFIED ALBUMIN AND SOLUBLE INTERCELLULAR ADHESION MOLECULE-1 IN PATIENTS WITH CORONARY HEART DISEASE — Research Paper | ScholarLens