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Effect of Anluohuaxianwan on hyperlipidemic fatty liver in rats

Xiumei Zhang

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Abstract

Purpose To observe the effects of Anluohuaxianwan on high fat diet-induced fatty liver in rats.Methods Rat fatty liver model was made by continuous feeding with high cholesterol forage for 4 weeks and then the animals were received different doses of Anluohuaxianwan for 4 weeks.General conditions,lanine aminotransferase(ALT) and superoxide dismutase(AST) activity,total cholesterol(TC) and triglyceride(TG) levels in serum were determined.TG and malondialdehyde(MDA) levels and superoxide dismutase(SOD) activity in liver homogenate and pathological changes in liver were also tested.Results Anluohuaxianwan treatment can significantly decrease serum ALT,AST and TC level,decrease the hepatic TG content,increase the hepatic SOD activity,and decrease the hepatic MDA level.The pathological observation results show that Anluohuaxianwan can significantly improve the pathological liver tissue damage of the alcoholic fatty liver.Conclusion Anluohuaxianwan has therapeutic effect on high fatty liver in rats.

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What this paper is about

Purpose To observe the effects of Anluohuaxianwan on high fat diet-induced fatty liver in rats.Methods Rat fatty liver model was made by continuous feeding with high cholesterol forage for 4 weeks and then the animals were received different doses of Anluohuaxianwan for 4 weeks.General conditions,lanine aminotransferase(ALT) and superoxide dismutase(AST) activity,total cholesterol(TC) and triglyceride(TG) levels in serum were determined.TG and malondialdehyde(MDA) levels and superoxide dismutase(SOD) activity in liver homogenate and pathological changes in liver were also tested.Results Anluohuaxianwan treatment can significantly decrease serum ALT,AST and TC level,decrease the hepatic TG content,increase the hepatic SOD activity,and decrease the hepatic MDA level.The pathological observation results show that Anluohuaxianwan can significantly improve the pathological liver tissue damage of the alcoholic fatty liver.Conclusion Anluohuaxianwan has therapeutic effect on high fatty liver in rats.

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Available abstract

Purpose To observe the effects of Anluohuaxianwan on high fat diet-induced fatty liver in rats.Methods Rat fatty liver model was made by continuous feeding with high cholesterol forage for 4 weeks and then the animals were received different doses of Anluohuaxianwan for 4 weeks.General conditions,lanine aminotransferase(ALT) and superoxide dismutase(AST) activity,total cholesterol(TC) and triglyceride(TG) levels in serum were determined.TG and malondialdehyde(MDA) levels and superoxide dismutase(SOD) activity in liver homogenate and pathological changes in liver were also tested.Results Anluohuaxianwan treatment can significantly decrease serum ALT,AST and TC level,decrease the hepatic TG content,increase the hepatic SOD activity,and decrease the hepatic MDA level.The pathological observation results show that Anluohuaxianwan can significantly improve the pathological liver tissue damage of the alcoholic fatty liver.Conclusion Anluohuaxianwan has therapeutic effect on high fatty liver in rats.

Key concepts: Malondialdehyde, Fatty liver, Superoxide dismutase, Triglyceride, Internal medicine, Pathological, Endocrinology, Chemistry

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