2010•Guide of China MedicineRequires access
The Effect of Combined Telmisartan with Alprostadil in Treating Early Diabetic Nephropathy
Lin Shao-xian
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Abstract
Objective To observe the effect of combined telmisartan with alprostadil in treating early diabetic nephropathy.Methods 56 patients with early diabetic nephropathy were divided into two groups randomly:conventional treatment group(n=28)and combined treatment group(n=28).Two groups of patients accept diabetes diet,control blood sugar,control blood pressure and adjusting blood-fat.Two groups were treated with telmisartan 80mg/day by oral administration and combined treatment group was treated with alprostadil 10μg/day by intravenous injection for 4 weeks.Urinary albumin excretion rate.serum creatinine,urea nitrogen were observed before and after treatment in two groups.Results Urinary albumin excretion rate was decreased obviously after combined telmisartan with alprostadil in treating early diabetic nephropathy.Conclusion Combined telmisartan with alprostadil in treating early diabetic nephropathy is an effective treatment.