Doxofylline plus Asaroneon for Chronic Obstructive Pulmonary Disease

Objective:To observe the efficacy of doxofylline and asarone on treatment of acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods:A total of 164 patients with AECOPD were randomly divided into two groups(82 cases) and control group(82 cases).The control group were treated with the low-flow oxygen,anti-inflammatory,anti-infective,correct water and electrolyte disturbance such as combined therapy.On the basis of the control group,the observation group were added with injection asarone and doxofylline in vein.Symptoms,signs and blood gas analysis were observed before and after the treatment.Results:The total effective rate of the observation group and control group were 93.9%and 81.7%,respectively(P0.05).the duration of fever,cough, expectoration,wheezing and 50%reduction in pulmonary rales in the observation group were significantly shorter than that in the control group(P0.01).FEV1,FEV1/FVC,PEF,PaO_2,PaCO_2 and other indicators in the observation group were also significantly better than that in the control group(P0.01).Conclusion:On the basis of conventional therapy,asarone combined doxofylline can improve the clinical efficacy in patients with AECOPD.