2011Zhongguo redai yixueRequires access

Analysis of drug sensitivity of candida to antifungal drugs in 152 infected patients

Fangqi Li

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Abstract

Aim To investigate drug sensitivity of candida to antibiotics in patients with candida infection.Methods Candida were isolated and cultured from clinical 152 and drug sensitivity of candida to antifungal was conducted and the results were analyzed.Results A total of 152(9.88%)candida strains were isolated from 1 538 samples,including 111 (73.03%) Candida albicans and 31(20.39%)Candida krusei.Candida albicans showed higher sensitive rates to conventional antifungal drugs except itraconazole.However,Candida krusei showed higher sensitive rates to antifungal agents.Conclusion Candida albicans and Candida krusei showed resistances to clinical first-line antifuangal drugs such as fluconazole.Thus srug sensitivity tests be carried out to guide clinical treatment of the infections.

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What this paper is about

Aim To investigate drug sensitivity of candida to antibiotics in patients with candida infection.Methods Candida were isolated and cultured from clinical 152 and drug sensitivity of candida to antifungal was conducted and the results were analyzed.Results A total of 152(9.88%)candida strains were isolated from 1 538 samples,including 111 (73.03%) Candida albicans and 31(20.39%)Candida krusei.Candida albicans showed higher sensitive rates to conventional antifungal drugs except itraconazole.However,Candida krusei showed higher sensitive rates to antifungal agents.Conclusion Candida albicans and Candida krusei showed resistances to clinical first-line antifuangal drugs such as fluconazole.Thus srug sensitivity tests be carried out to guide clinical treatment of the infections.

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Available abstract

Aim To investigate drug sensitivity of candida to antibiotics in patients with candida infection.Methods Candida were isolated and cultured from clinical 152 and drug sensitivity of candida to antifungal was conducted and the results were analyzed.Results A total of 152(9.88%)candida strains were isolated from 1 538 samples,including 111 (73.03%) Candida albicans and 31(20.39%)Candida krusei.Candida albicans showed higher sensitive rates to conventional antifungal drugs except itraconazole.However,Candida krusei showed higher sensitive rates to antifungal agents.Conclusion Candida albicans and Candida krusei showed resistances to clinical first-line antifuangal drugs such as fluconazole.Thus srug sensitivity tests be carried out to guide clinical treatment of the infections.

Key concepts: Candida krusei, Candida albicans, Fluconazole, Itraconazole, Microbiology, Candida infections, Antifungal drug, Antifungal drugs

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