The infection distribution and sensitive analysis on candida albicans

Objective To analyze clinical distribution and the drug sensitive characteristics of the infection caused by candida albicans in hospitals,and to provide evidence for the clinical use of antifungal drugs.Methods 497 fungi were isolated from samples collected in the hospital from September 2007 to December 2008,Bacterial identification and drug sensitivity test by ATB expression instrument and its supporting plank were used to test the fungi,and then the result was analyzed.Results Most of the 497 strains were candida,and the first three were candida albicans 54.3%(270/497),candida tropicalis 18.5%(92/497) as well as candida glabrata 6.2%(31/497).The sensitivity rates of candida to 5-fluorocytosine,amphotericin B,itraconazole,fluconazole,voriconazole were 96.7%,94.4%,93.8%,86.8%,84.6% respectively.Conclusion The infected patients are mainly in respiratory department,digestion medicine department,ICU,oncology department,and cardiology department.And the main cause of infection was candida albican,followed by the candida tropicalis and candida glabrata.The sensitivity rates of candida to 5-fluorocytosine and amphotericin B are high,however,drug resistance to itraconazole and fluconazole was generated.