Triple Combined Regimen of Rabeprazole and Levofloxacin,Rrnidazole Therapy for Peptic Ulcer

Objective To evaluate the therapeutic effect of triple therapy of rabeprazole and levofloxacin,ornidazole combined for peptic ulcer.Methods 80 patients with helicobacter pylori(HP) infection sufferedfrom peptic ulcer were randomly divided into treatment group and control group.Treatment group 40 cases were administrated rabeprazole(10mg,twice a day),levofloxacin(200mg,three times a day) and ornidazole(500mg,twice a day) for two weeks;Control group 40 cases were treated with omeprazole(20mg,twice a day),amoxicillin(500mg,three times a day) and metronidazole(200 mg,three times a day) for two weeks.Four weeks later,The HP eradication rate was observed.Results The HP eradication rate of the treatment group was 90.0%(36/40),while that of the control group was 72.5%(29/40),there was significant differencebetween two groups(χ2=4.02,P0.05).Conclusion Triple therapy of rabeprazole and levofloxacin,ornidazole combined is one of the ideal methods for HP infection suffered from peptic ulcer.