The therapeutic effect of triple combined regimen of Rabeprazole and Levofloxacin,Amoxicill therapy for peptic ulcer

Objective To evaluate the therapeutic effect of triple therapy of Rabeprazole and Levofloxacin,Amoxicill combined for peptic ulcer.Methods 120 patients with helicobacter pylori(Hp)infection suffered from peptic ulcer were randomly divided into observation group and control group,60 cases in each group.Observation group were administrated Rabeprazole(10 mg,twice a day),Levofloxacin(200 mg,twice a day)and Amoxicill(1000 mg,twice a day)for two weeks.Control group were treated with Omeprazole(20 mg,twice a day),Amoxicillin(500 mg,twice a day)and Clarithromycin(200 mg,twice a day)for two weeks.Four weeks later,the Hp eradication rate and the total effective rate were observed.Results After the treatment the total effective rate of the observation group was 95%,while that of the control group was 80%,the dfferences were statistically significant(P0.05).The Hp eradication rate of the observation group was 90.0%,while that of the control group was 70%,there was significant difference between two groups(P0.05).Conclusion Triple therapy of Rabeprazole and Levofloxacin,Omidazole combined is an effective method at the same time is one of the ideal methods for Hp infection suffered from peptic ulcer.