Analysis of the value of hematology analyzer in the laboratory quality control

Objective To evaluate the accuracy and uniformity of the routine examination with the same brand but different type hematology analyzers in daily work. Methods The KX-21A was chosen as the target analyzer.A sample of fresh whole blood was tested ten times independly with the five hematology analyzers in order to gain the precision and the correction coefficient.Nine fresh whole blood samples of three levels of the WBC,RBC(Hb),and PLT were examinated three times respectively on each of the five analyzers.The original parameters of the WBC,RBC(Hb),PLT were calibrated with the correction coefficient,then repeating the above progress with the nine samples. Results ①The precision of the five hematology analyzers are fine.②Before being corrected,the correlation coefficient of the target analyzer and the other analyzers were no less than 0.9990 with 11 difference percentage exceeding the acceptable limit in the comparison tests.③After being calibrated the correlaion coefficient between the target analyzer and the others were no less than 0.9999 with all difference percentage being in the acceptable limit in the comparison tests. Conclusion ①The systematic error between machines timely can be found through comparison tests of hematology analyzers with fresh whole blood.②It can improve the accuracy and uniformity of results of the hematology analyzers in the same laboratory through correcting the parameters of the hematology analyzers with fresh blood.