Comparative study on fresh blood detection by different hematology analyzers

Objective To evaluate the veracity and consistency of the results obtained from four automated hematology analyzers.Methods The reproducibility tests were used to assess the precision,the verification tests were exerted to evaluate the accuracy and consistency of test parameters(WBC,RBC,HGB,MCV and PLT) of the four hematology analyzers.According to the 1/2 standard of American Clinical Laboratory Improvement Amendment(CLIA,88),the relative bias of the reference analyzer and other assessed analyzers were determined.Results The results obtained from the four analyzers showed excellent precision and stability,the coefficients of variation(CV) were all less than 5%;compared with the results of ABX120,the results of ABX80,CD3700 and BC5300 showed excellent correlation,all coefficients of correlation(γ)exceeded 0.975.The results of both RBC and HGB obtained from CD3700 and BC5300 exceeded allowable error;other results were in the allowable error range.Conclusion In the condition of the excellent precision and stability,system errors existed in the analyzer can be found by verification on time.Through being adjusted and calibrated,the hematology analyzers can meet the requirements and these results are consistent.